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KMID : 0614620120600030172
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Korean Journal of Gastroenterology
2012 Volume.60 No. 3 p.172 ~ p.176
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Intestinal Amyloidosis with Intractable Diarrhea and Intestinal Pseudo-obstruction
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Kim Yeon-Ju
Kim Hyun-Soo
Park Sun-Young
Park Sang-Woo
Choi Yoo-Duk
Park Chang-Hwan
Choi Sung-Kyu
Rew Jong-Sun
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Abstract
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We report herein a case of intestinal amyloidosis with grave prognosis that caused intractable diarrhea and intestinal pseudo-obstruction, alternately in spite of intensive conservative treatment. A 44-year-old woman was admitted for fever, diarrhea, and crampy abdominal pain which had been continuned during 6 months. Abdomen CT scan showed edematous wall thickening of the small bowel and right colon, and colonoscopic biopsy revealed amyloid deposition in the mucosa. Monoclonal light chains in serum and/or urine were not detected and highly elevated serum amyloid A was shown. In spite of intensive treatment including oral prednisolone and colchicine, diarrhea and intestinal pseudo-obstruction developed alternately, general status rapidly got worsened and died after two months.
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KEYWORD
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Amyloidosis, Diarrhea, Intestinal pseudo-obstruction
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